内容紹介
Genetic Counseling of HBOC and Japanese Organization of HBOC
Summary
Genetic testing, which reveals germline mutations, is extremely important for HBOC patients and their families. The evolution of this field has created a need for accurate cancer genetic counseling and risk assessment. Prevention and early therapy are possible in HBOC. If a patient has BRCA1 or BRCA2 mutations, the at-risk relatives should receive the information through genetic counseling. Genetic counseling provides not only information but also psychological and social support so that the patient or subject can autonomously decide. Clinical practice for the treatment of HBOC needs a multidisciplinary network that includes clinical geneticists, breast cancer surgeons, and ovarian cancer surgeons. Thus, the Japan Society of Human Genetics, Japan Breast Cancer Society, and Japan Society of Obstetrics and Gynecology established a new corporation named Japanese Organization of HBOC(JOHBOC)for a HBOC comprehensive medical care system.
要旨
遺伝性乳癌卵巣癌(HBOC)の診療には,乳腺部門,婦人科腫瘍部門だけではなく遺伝カウンセリングを行う臨床遺伝部門との連携が必要である。これら3部門の連携を中心とするHBOCの診療体制を全国的に整備拡充させるため,日本乳癌学会,日本産科婦人科学会および日本人類遺伝学会が中心となり,2016年に日本遺伝性乳癌卵巣癌総合診療制度機構(Japanese Organization of Hereditary Breast and Ovarian Cancer: JOHBOC)を発足させ,HBOCの包括的医療の推進を図っている。
目次
Summary
Genetic testing, which reveals germline mutations, is extremely important for HBOC patients and their families. The evolution of this field has created a need for accurate cancer genetic counseling and risk assessment. Prevention and early therapy are possible in HBOC. If a patient has BRCA1 or BRCA2 mutations, the at-risk relatives should receive the information through genetic counseling. Genetic counseling provides not only information but also psychological and social support so that the patient or subject can autonomously decide. Clinical practice for the treatment of HBOC needs a multidisciplinary network that includes clinical geneticists, breast cancer surgeons, and ovarian cancer surgeons. Thus, the Japan Society of Human Genetics, Japan Breast Cancer Society, and Japan Society of Obstetrics and Gynecology established a new corporation named Japanese Organization of HBOC(JOHBOC)for a HBOC comprehensive medical care system.
要旨
遺伝性乳癌卵巣癌(HBOC)の診療には,乳腺部門,婦人科腫瘍部門だけではなく遺伝カウンセリングを行う臨床遺伝部門との連携が必要である。これら3部門の連携を中心とするHBOCの診療体制を全国的に整備拡充させるため,日本乳癌学会,日本産科婦人科学会および日本人類遺伝学会が中心となり,2016年に日本遺伝性乳癌卵巣癌総合診療制度機構(Japanese Organization of Hereditary Breast and Ovarian Cancer: JOHBOC)を発足させ,HBOCの包括的医療の推進を図っている。