内容紹介
Clinical Outcome of Eight Patients with Perforated Colorectal Cancer
Summary
We studied the clinicopathological findings of 8 patients with perforated colorectal cancer. Four patients were male. In 7 patients, the primary cancer site was left side colon. Chief complaints were abdominal pain in 7 patients and diarrhea in 1 patient. The emergent operation was performed in all cases. The final stages of 8 patients were as follows: 5 patients with StageⅡ, 2 patients with Stage Ⅲ, 1 patient with Stage Ⅳ. All patients were discharged from our hospital. Postoperative chemotherapy was performed for 5 patients. Of these 8 patients, 1 patient had peritoneal dissemination and 1 patient had local recurrence. Two patients were died of cancer and 6 patients were alive. In conclusion, patient with perforated colorectal cancer were high risk cases for recurrence.
要旨
目的: 当科で2005年1月～2016年12月までに経験した大腸癌部穿孔8症例の特徴について検討した。結果: 男性4例,女性4例,平均年齢66.5歳。癌の部位は上行結腸1例,S状結腸5例,直腸RSが2例であった。主訴は7例が腹痛,1例が下痢。全例で緊急手術を施行した。進行度はStage Ⅱ5例,Stage Ⅲ2例,Stage Ⅳが1例。転帰は全例で軽快に退院した。退院後に化学療法を施行した症例は5例。2例に再発を認め,腹膜播種1例,局所再発が1例であった。予後は2例が癌死,1例が再発生存中で,5例が無再発生存中である。まとめ: 再発形式を検討すると腹膜播種・局所再発であり,癌細胞を含む腸管内容の漏出からと考えられた。StageⅡの再発高危険群のリスク因子に穿孔も含まれており,再発予防の術後補助化学療法が考慮される。
目次
Summary
We studied the clinicopathological findings of 8 patients with perforated colorectal cancer. Four patients were male. In 7 patients, the primary cancer site was left side colon. Chief complaints were abdominal pain in 7 patients and diarrhea in 1 patient. The emergent operation was performed in all cases. The final stages of 8 patients were as follows: 5 patients with StageⅡ, 2 patients with Stage Ⅲ, 1 patient with Stage Ⅳ. All patients were discharged from our hospital. Postoperative chemotherapy was performed for 5 patients. Of these 8 patients, 1 patient had peritoneal dissemination and 1 patient had local recurrence. Two patients were died of cancer and 6 patients were alive. In conclusion, patient with perforated colorectal cancer were high risk cases for recurrence.
要旨
目的: 当科で2005年1月～2016年12月までに経験した大腸癌部穿孔8症例の特徴について検討した。結果: 男性4例,女性4例,平均年齢66.5歳。癌の部位は上行結腸1例,S状結腸5例,直腸RSが2例であった。主訴は7例が腹痛,1例が下痢。全例で緊急手術を施行した。進行度はStage Ⅱ5例,Stage Ⅲ2例,Stage Ⅳが1例。転帰は全例で軽快に退院した。退院後に化学療法を施行した症例は5例。2例に再発を認め,腹膜播種1例,局所再発が1例であった。予後は2例が癌死,1例が再発生存中で,5例が無再発生存中である。まとめ: 再発形式を検討すると腹膜播種・局所再発であり,癌細胞を含む腸管内容の漏出からと考えられた。StageⅡの再発高危険群のリスク因子に穿孔も含まれており,再発予防の術後補助化学療法が考慮される。