内容紹介
A Case of Thyroid Metastasis from Rectal Cancer
Summary
The patient was a 68-year-old man who underwent Hartmann's procedure for a fistula due to rectal cancer in August 2012. The cancer was tub2>tub1, pSE, pN2, pH2, pM1(intrapulmonary metastasis), stage Ⅳ. The patient received 5 courses of FOLFOX and bevacizumab as adjuvant chemotherapy. In December 2012, the patient was seen by Otolaryngology for hoarseness. A neck examination revealed induration of the left lobe of the thyroid, and FNA biopsy strongly suggested metastasis of rectal cancer to the thyroid. FDG-PET was performed and revealed extensive accumulation of FDG at the same site. The patient was diagnosed with thyroid metastasis of rectal cancer and underwent a left thyroid lobectomy and lymph node dissection in January 2013. Histopathology confirmed the thyroid metastasis of rectal cancer. Thyroid metastasis of rectal cancer is extremely rare: there are 11 such cases in the Japanese literature, including the case encountered by the current authors. This case is reported here, along with a discussion of some of the literature.
要旨
症例は68歳,男性。2012年8月,直腸癌穿孔にてハルトマン手術を施行した。tub2>tub1,pSE,pN2,pH2,pM1(肺),stage Ⅳであった。術後補助化学療法としてbevacizumab(BV)+FOLFOX療法を5コース行った。12月に嗄声の訴えあり,耳鼻科を受診した。頸部診察にて甲状腺左葉に硬結を指摘され,FNAの結果,直腸癌の甲状腺転移を疑われた。FDG-PETを施行し,同部位へのFDGの高度集積を認めた。直腸癌甲状腺転移の診断で,2013年1月甲状腺左葉切除,リンパ節郭清を行った。病理組織学的に直腸癌の甲状腺転移であった。直腸癌甲状腺転移は非常にまれで,本邦論文報告例は自験例を含め11例であり,若干の文献的考察を加え報告する。
目次
Summary
The patient was a 68-year-old man who underwent Hartmann's procedure for a fistula due to rectal cancer in August 2012. The cancer was tub2>tub1, pSE, pN2, pH2, pM1(intrapulmonary metastasis), stage Ⅳ. The patient received 5 courses of FOLFOX and bevacizumab as adjuvant chemotherapy. In December 2012, the patient was seen by Otolaryngology for hoarseness. A neck examination revealed induration of the left lobe of the thyroid, and FNA biopsy strongly suggested metastasis of rectal cancer to the thyroid. FDG-PET was performed and revealed extensive accumulation of FDG at the same site. The patient was diagnosed with thyroid metastasis of rectal cancer and underwent a left thyroid lobectomy and lymph node dissection in January 2013. Histopathology confirmed the thyroid metastasis of rectal cancer. Thyroid metastasis of rectal cancer is extremely rare: there are 11 such cases in the Japanese literature, including the case encountered by the current authors. This case is reported here, along with a discussion of some of the literature.
要旨
症例は68歳,男性。2012年8月,直腸癌穿孔にてハルトマン手術を施行した。tub2>tub1,pSE,pN2,pH2,pM1(肺),stage Ⅳであった。術後補助化学療法としてbevacizumab(BV)+FOLFOX療法を5コース行った。12月に嗄声の訴えあり,耳鼻科を受診した。頸部診察にて甲状腺左葉に硬結を指摘され,FNAの結果,直腸癌の甲状腺転移を疑われた。FDG-PETを施行し,同部位へのFDGの高度集積を認めた。直腸癌甲状腺転移の診断で,2013年1月甲状腺左葉切除,リンパ節郭清を行った。病理組織学的に直腸癌の甲状腺転移であった。直腸癌甲状腺転移は非常にまれで,本邦論文報告例は自験例を含め11例であり,若干の文献的考察を加え報告する。