内容紹介
Summary
Here we report 2 cases of neuroendocrine carcinoma(NEC)of the non-ampullary duodenum which is extremely rare neoplasm. Case 1: A 76-year-old man had a type 2 duodenal carcinoma with a 3 cm-sized lymph node metastasis. Duodenal resection with subpyloric lymph nodes dissection and Roux-en-Y reconstruction were performed. The histopathological diagnosis was NEC of the duodenal bulb after surgery(pT3pN1M0, stage ⅢA, UICC 7th edition). The patient died of chronic heart failure 10 years and 3 months after the surgery. Case 2: A 45-year-old woman had a type 2 duodenal NEC of the second part of the duodenum. A subtotal stomach-preserving pancreatoduodenectomy was performed with lymph node dissection.(pT4pN0M0, stageⅡB, UICC 7th edition). The patient died of recurrence 7 months after the surgery.
要旨
乳頭部を除いた十二指腸原発の神経内分泌癌は報告例が少ない。われわれは,球部と下行脚に発生した十二指腸神経内分泌癌をそれぞれ1例経験した。症例1: 患者は76歳,男性。径3 cm大のリンパ節転移を伴う球部後壁の2型の十二指腸癌の診断で,十二指腸部分切除かつ転移リンパ節切除を施行し,術後に神経内分泌癌と診断された(pT3pN1M0,stage ⅢA,UICC第7版)。術後10年3か月で慢性心不全の増悪により死亡した。症例2: 患者は45歳,女性。十二指腸下行脚の1/2周性の2型の十二指腸神経内分泌癌であった。亜全胃温存膵頭十二指腸切除術を施行した(pT4pN0M0,stageⅡB,UICC第7版)。術後再発にて術後7か月で死亡した。
目次
Here we report 2 cases of neuroendocrine carcinoma(NEC)of the non-ampullary duodenum which is extremely rare neoplasm. Case 1: A 76-year-old man had a type 2 duodenal carcinoma with a 3 cm-sized lymph node metastasis. Duodenal resection with subpyloric lymph nodes dissection and Roux-en-Y reconstruction were performed. The histopathological diagnosis was NEC of the duodenal bulb after surgery(pT3pN1M0, stage ⅢA, UICC 7th edition). The patient died of chronic heart failure 10 years and 3 months after the surgery. Case 2: A 45-year-old woman had a type 2 duodenal NEC of the second part of the duodenum. A subtotal stomach-preserving pancreatoduodenectomy was performed with lymph node dissection.(pT4pN0M0, stageⅡB, UICC 7th edition). The patient died of recurrence 7 months after the surgery.
要旨
乳頭部を除いた十二指腸原発の神経内分泌癌は報告例が少ない。われわれは,球部と下行脚に発生した十二指腸神経内分泌癌をそれぞれ1例経験した。症例1: 患者は76歳,男性。径3 cm大のリンパ節転移を伴う球部後壁の2型の十二指腸癌の診断で,十二指腸部分切除かつ転移リンパ節切除を施行し,術後に神経内分泌癌と診断された(pT3pN1M0,stage ⅢA,UICC第7版)。術後10年3か月で慢性心不全の増悪により死亡した。症例2: 患者は45歳,女性。十二指腸下行脚の1/2周性の2型の十二指腸神経内分泌癌であった。亜全胃温存膵頭十二指腸切除術を施行した(pT4pN0M0,stageⅡB,UICC第7版)。術後再発にて術後7か月で死亡した。