内容紹介
Summary
We report a case of a simultaneous and ipsilateral multiple breast carcinoma. The patient was 35-year-old woman. She was noticed a breast lump on her right breast, and visited our hospital. Mammography showed a tumor accompanied by spiculation on her right breast. Ultrasonography revealed 2 tumors with irregular margins, 23 mm in diameter and 12 mm in diameter, and were observed on C area of her right breast. The continuity of the 2 tumors was not clear. Core needle biopsies for each breast tumors led to a diagnosis. The pathological diagnosis was invasive ductal carcinoma. We checked up whole body. There was no metastatic lesion. We performed breast conserving surgery and sentinel node biopsy. The pathological diagnosis was invasive ductal carcinoma, positive for estrogen receptor and progesterone receptor, negative for HER2/neu. The Ki-67 positive cell index was 30%. The surgical margin was negative. We diagnosed T2N0M0=StageⅡA. She was started the endocrine therapy by LH-RH agonist and tamoxifen. Four years after surgery, she was well without metastases.
要旨
若年者同時性・同側性多発乳癌に対し乳房温存手術を施行した症例を経験した。症例は35歳,女性。マンモグラフィ検査では右UO領域にspiculationを伴う腫瘤陰影を認めた。超音波検査では右乳房C領域に直径23 mmと12 mmの形状不整・境界不明瞭な腫瘍を2個認めた。二つの腫瘍の連続性は明らかでなかった。2か所の針生検の結果,両方ともに浸潤性乳管癌と診断され,T2N0M0=StageⅡAの術前診断で,乳房温存手術+センチネルリンパ節生検術を施行した。病理組織診断では,直径21 mmの腫瘍は浸潤性乳管癌(硬癌),ER陽性,PgR陽性,HER2陰性,Ki-67 30%,直径15 mmの腫瘍は浸潤性乳管癌(硬癌),ER陽性,PgR陽性,HER2陰性,Ki-67 30%と診断された。両腫瘍間には病理学的に連続性は認めず,切除断端は陰性であった。LH-RH agonistと2年間,tamoxifenを5年間の予定で投与している。術後4年目の現在,無再発生存中である。
目次
We report a case of a simultaneous and ipsilateral multiple breast carcinoma. The patient was 35-year-old woman. She was noticed a breast lump on her right breast, and visited our hospital. Mammography showed a tumor accompanied by spiculation on her right breast. Ultrasonography revealed 2 tumors with irregular margins, 23 mm in diameter and 12 mm in diameter, and were observed on C area of her right breast. The continuity of the 2 tumors was not clear. Core needle biopsies for each breast tumors led to a diagnosis. The pathological diagnosis was invasive ductal carcinoma. We checked up whole body. There was no metastatic lesion. We performed breast conserving surgery and sentinel node biopsy. The pathological diagnosis was invasive ductal carcinoma, positive for estrogen receptor and progesterone receptor, negative for HER2/neu. The Ki-67 positive cell index was 30%. The surgical margin was negative. We diagnosed T2N0M0=StageⅡA. She was started the endocrine therapy by LH-RH agonist and tamoxifen. Four years after surgery, she was well without metastases.
要旨
若年者同時性・同側性多発乳癌に対し乳房温存手術を施行した症例を経験した。症例は35歳,女性。マンモグラフィ検査では右UO領域にspiculationを伴う腫瘤陰影を認めた。超音波検査では右乳房C領域に直径23 mmと12 mmの形状不整・境界不明瞭な腫瘍を2個認めた。二つの腫瘍の連続性は明らかでなかった。2か所の針生検の結果,両方ともに浸潤性乳管癌と診断され,T2N0M0=StageⅡAの術前診断で,乳房温存手術+センチネルリンパ節生検術を施行した。病理組織診断では,直径21 mmの腫瘍は浸潤性乳管癌(硬癌),ER陽性,PgR陽性,HER2陰性,Ki-67 30%,直径15 mmの腫瘍は浸潤性乳管癌(硬癌),ER陽性,PgR陽性,HER2陰性,Ki-67 30%と診断された。両腫瘍間には病理学的に連続性は認めず,切除断端は陰性であった。LH-RH agonistと2年間,tamoxifenを5年間の予定で投与している。術後4年目の現在,無再発生存中である。