内容紹介
Summary
Case 1 is a 68-year-old woman with locally recurrent rectal cancer(LRRC)developed 5 years after resection of primary rectal cancer. The tumor seized right lateral side in pelvic. We performed tumor excision after preoperative chemoradiation comprised external beam radiation with oral S-1(tegafur/gimeracil/oteracil). He has been relapse-free for 3 years 3 months after surgery. Case 2 is a 74-year-old man with LRRC developed 2 years after resection of primary rectal cancer. The tumor was located dorsal to anastomosis site in pelvic. We performed abdominoperineal resection for LRRC after preoperative chemoradiation with oral S-1. He has been relapse-free for 2 years. It was suggested that preoperative radiotherapy combined with oral FU for local recurrence after rectal cancer may contribute to distant and local control.
要旨
症例1は68歳,女性。直腸癌(Rb)術後5年目に骨盤右側方に局所再発が認められた。術前放射線化学療法を施行し開腹下に腫瘍切除を施行し(R0),病理学的治療効果はGrade 3であった。術後3年3か月無再発経過中である。症例2は74歳,男性。直腸癌(Rb)術後2年目に吻合部背側に局所再発が認められた。術前放射線化学療法を施行後に腹会陰式直腸切断術を施行し(R0),病理学的治療効果はGrade 2であった。術後2年無再発経過中である。孤立性直腸癌術後局所再発に対する経口FU剤併用術前放射線化学療法は,遠隔および局所制御に寄与する可能性が示唆された。
目次
Case 1 is a 68-year-old woman with locally recurrent rectal cancer(LRRC)developed 5 years after resection of primary rectal cancer. The tumor seized right lateral side in pelvic. We performed tumor excision after preoperative chemoradiation comprised external beam radiation with oral S-1(tegafur/gimeracil/oteracil). He has been relapse-free for 3 years 3 months after surgery. Case 2 is a 74-year-old man with LRRC developed 2 years after resection of primary rectal cancer. The tumor was located dorsal to anastomosis site in pelvic. We performed abdominoperineal resection for LRRC after preoperative chemoradiation with oral S-1. He has been relapse-free for 2 years. It was suggested that preoperative radiotherapy combined with oral FU for local recurrence after rectal cancer may contribute to distant and local control.
要旨
症例1は68歳,女性。直腸癌(Rb)術後5年目に骨盤右側方に局所再発が認められた。術前放射線化学療法を施行し開腹下に腫瘍切除を施行し(R0),病理学的治療効果はGrade 3であった。術後3年3か月無再発経過中である。症例2は74歳,男性。直腸癌(Rb)術後2年目に吻合部背側に局所再発が認められた。術前放射線化学療法を施行後に腹会陰式直腸切断術を施行し(R0),病理学的治療効果はGrade 2であった。術後2年無再発経過中である。孤立性直腸癌術後局所再発に対する経口FU剤併用術前放射線化学療法は,遠隔および局所制御に寄与する可能性が示唆された。