内容紹介
Summary
Metastasis of renal cell carcinoma to the pancreas is a relatively rare condition. We encountered 2 such cases. The first case was a 72-year-old man who underwent a left nephrectomy owing to left renal cancer in 2005. An abdominal dynamic CT scan 12 years after surgery revealed tumors in the pancreatic body and right kidney. A PET-CT scan revealed low intensity uptake of both tumors, and therefore, metastasis of the left renal cell carcinoma to the pancreas was suspected. We then performed partial resections of the pancreatic tail and right kidney. Pathologic findings confirmed that the pancreatic tumor and right renal tumor were metastases of the left renal cell carcinoma. The postoperative course was favorable, and the patient has been followed up in an outpatient setting for 10 months with no signs of recurrence. The second case was a 51-year-old woman with tumors in the left kidney and pancreatic head that were detected by abdominal contrast CT and MRI. We diagnosed the patient with left renal cell carcinoma with metastasis to the pancreas. We performed a radical nephrectomy of the left kidney and full pancreatectomy. Pathologic findings confirmed left renal cell carcinoma, pStage Ⅳ, with metastasis to the pancreas. The postoperative course was favorable without recurrence for 14 years. We report on two cases of metastasis of renal cell carcinoma to the pancreas in patients who underwent radical resections and had favorable postoperative courses, with some bibliographic consideration.
要旨
腎癌の膵転移は比較的まれな病態である。今回われわれは,腎癌の膵転移を来した2例を経験した。症例1は72歳,男性。2005年,左腎癌にて左腎全摘出術を施行した。術後12年目に腹部dynamic CT検査で膵体部および右腎に腫瘍を指摘された。PET-CT検査にて,膵体部腫瘍および右腎に淡い集積を認めた。左腎癌膵転移の疑いにて,開腹膵体尾部切除術および右腎部分切除術を施行した。病理結果にて,膵腫瘍,右腎腫瘍は左腎癌の転移であった。術後経過は良好であり,現在外来で10か月間,無再発経過観察中である。症例2は51歳,女性。腹部造影CT,MRI検査にて左腎,膵頭部に腫瘍を認めた。左腎癌および膵転移の診断の下,根治的左腎摘出術,膵全摘術を施行した。病理結果は左腎癌,膵転移にてpStage Ⅳであった。術後経過は良好であり,14年間無再発で経過している。腎癌の膵転移に対して根治的切除術を行い,良好な経過をたどった2例を経験したので若干の文献的考察を加えて報告する。
目次
Metastasis of renal cell carcinoma to the pancreas is a relatively rare condition. We encountered 2 such cases. The first case was a 72-year-old man who underwent a left nephrectomy owing to left renal cancer in 2005. An abdominal dynamic CT scan 12 years after surgery revealed tumors in the pancreatic body and right kidney. A PET-CT scan revealed low intensity uptake of both tumors, and therefore, metastasis of the left renal cell carcinoma to the pancreas was suspected. We then performed partial resections of the pancreatic tail and right kidney. Pathologic findings confirmed that the pancreatic tumor and right renal tumor were metastases of the left renal cell carcinoma. The postoperative course was favorable, and the patient has been followed up in an outpatient setting for 10 months with no signs of recurrence. The second case was a 51-year-old woman with tumors in the left kidney and pancreatic head that were detected by abdominal contrast CT and MRI. We diagnosed the patient with left renal cell carcinoma with metastasis to the pancreas. We performed a radical nephrectomy of the left kidney and full pancreatectomy. Pathologic findings confirmed left renal cell carcinoma, pStage Ⅳ, with metastasis to the pancreas. The postoperative course was favorable without recurrence for 14 years. We report on two cases of metastasis of renal cell carcinoma to the pancreas in patients who underwent radical resections and had favorable postoperative courses, with some bibliographic consideration.
要旨
腎癌の膵転移は比較的まれな病態である。今回われわれは,腎癌の膵転移を来した2例を経験した。症例1は72歳,男性。2005年,左腎癌にて左腎全摘出術を施行した。術後12年目に腹部dynamic CT検査で膵体部および右腎に腫瘍を指摘された。PET-CT検査にて,膵体部腫瘍および右腎に淡い集積を認めた。左腎癌膵転移の疑いにて,開腹膵体尾部切除術および右腎部分切除術を施行した。病理結果にて,膵腫瘍,右腎腫瘍は左腎癌の転移であった。術後経過は良好であり,現在外来で10か月間,無再発経過観察中である。症例2は51歳,女性。腹部造影CT,MRI検査にて左腎,膵頭部に腫瘍を認めた。左腎癌および膵転移の診断の下,根治的左腎摘出術,膵全摘術を施行した。病理結果は左腎癌,膵転移にてpStage Ⅳであった。術後経過は良好であり,14年間無再発で経過している。腎癌の膵転移に対して根治的切除術を行い,良好な経過をたどった2例を経験したので若干の文献的考察を加えて報告する。