内容紹介
Summary
The present study reports the case of a 49-year-old woman who was diagnosed with cancer of the left breast at the age of 43 years. Following chemotherapy, the patient had undergone partial mastectomy and axillary lymphadenectomy. Postoperatively, she underwent radiotherapy and hormone therapy. Five years and 4 months after the operation, the patient developed pain in the cervical vertebrae and was diagnosed with spinal metastasis. During the period, she began experiencing fatigue and hematological investigations indicated anemia, as well as thrombocytopenia, jaundice, and schistocytes. The patient was referred to our facility for further examination and treatment. On investigation, she was diagnosed with cancer-related thrombotic microangiopathy(TMA). The patient was advised to undergo chemotherapy due to which symptoms of TMA were relieved. She continued to receive chemotherapy for the following 3 years and 2 months until her death.
要旨
症例は49歳,女性。43歳時に左乳癌と診断され,化学療法の後に乳房部分切除術および腋窩リンパ節郭清術が施行された。術後は温存乳房照射およびホルモン療法が行われた。 術後5年4か月目に頸椎の痛みが出現し, 頸椎転移の診断となった。同時期より倦怠感の出現を認め,血液生化学所見では著明な貧血や血小板減少,黄疸,破砕赤血球の出現を指摘され,精査加療目的に当院へ紹介となった。精査にて,再発乳癌に伴う血栓性微小血管症(thrombotic microangiopathy: TMA)と診断された。化学療法を開始したところ,TMAの病態の軽減を図ることが可能となった。その後も化学療法を継続し,約3年2か月後に死亡した。
目次
The present study reports the case of a 49-year-old woman who was diagnosed with cancer of the left breast at the age of 43 years. Following chemotherapy, the patient had undergone partial mastectomy and axillary lymphadenectomy. Postoperatively, she underwent radiotherapy and hormone therapy. Five years and 4 months after the operation, the patient developed pain in the cervical vertebrae and was diagnosed with spinal metastasis. During the period, she began experiencing fatigue and hematological investigations indicated anemia, as well as thrombocytopenia, jaundice, and schistocytes. The patient was referred to our facility for further examination and treatment. On investigation, she was diagnosed with cancer-related thrombotic microangiopathy(TMA). The patient was advised to undergo chemotherapy due to which symptoms of TMA were relieved. She continued to receive chemotherapy for the following 3 years and 2 months until her death.
要旨
症例は49歳,女性。43歳時に左乳癌と診断され,化学療法の後に乳房部分切除術および腋窩リンパ節郭清術が施行された。術後は温存乳房照射およびホルモン療法が行われた。 術後5年4か月目に頸椎の痛みが出現し, 頸椎転移の診断となった。同時期より倦怠感の出現を認め,血液生化学所見では著明な貧血や血小板減少,黄疸,破砕赤血球の出現を指摘され,精査加療目的に当院へ紹介となった。精査にて,再発乳癌に伴う血栓性微小血管症(thrombotic microangiopathy: TMA)と診断された。化学療法を開始したところ,TMAの病態の軽減を図ることが可能となった。その後も化学療法を継続し,約3年2か月後に死亡した。