内容紹介
Summary
A 63-year-old woman was admitted to our hospital owing to advanced rectal carcinoma. The patient underwent laparoscopic low anterior resection with D3 lymph node dissection and partial resection of the uterus. The histopathological diagnosis was fT4bN2M0, fStage Ⅲb. Thus, capecitabine plus oxaliplatin(CapeOX)therapy as adjuvant chemotherapy was scheduled for 6 months. However, after the 4th course of chemotherapy, contrast-enhanced CT revealed multiple metastases of the rectal carcinoma including metastases in the liver, peritoneum, retroperitoneum, and subcutaneous tissue of the left lower back. The patient received palliative treatment and died 8 months after surgery. Only a few cases of subcutaneous metastasis of rectal carcinoma have been reported. Therefore, we herein report this case with a review of the literature.
要旨
症例は63歳,女性。下血を認め近医を受診した。下部消化管内視鏡検査にて直腸癌と診断され,当院に紹介となった。腹腔鏡下低位前方切除術を施行し,病理診断はpT4b(uterus)N2M0,pStage Ⅲbであった。術後補助療法にcapecitabine+oxaliplatin(CapeOX)療法を施行した。4コース後に肝転移,腹膜播種および左腰部に皮下転移を認めた。皮下病変の針生検により免疫組織学的に転移と確認された。術後から8か月で死亡した。直腸癌の皮下転移は比較的まれであり報告する。
目次
A 63-year-old woman was admitted to our hospital owing to advanced rectal carcinoma. The patient underwent laparoscopic low anterior resection with D3 lymph node dissection and partial resection of the uterus. The histopathological diagnosis was fT4bN2M0, fStage Ⅲb. Thus, capecitabine plus oxaliplatin(CapeOX)therapy as adjuvant chemotherapy was scheduled for 6 months. However, after the 4th course of chemotherapy, contrast-enhanced CT revealed multiple metastases of the rectal carcinoma including metastases in the liver, peritoneum, retroperitoneum, and subcutaneous tissue of the left lower back. The patient received palliative treatment and died 8 months after surgery. Only a few cases of subcutaneous metastasis of rectal carcinoma have been reported. Therefore, we herein report this case with a review of the literature.
要旨
症例は63歳,女性。下血を認め近医を受診した。下部消化管内視鏡検査にて直腸癌と診断され,当院に紹介となった。腹腔鏡下低位前方切除術を施行し,病理診断はpT4b(uterus)N2M0,pStage Ⅲbであった。術後補助療法にcapecitabine+oxaliplatin(CapeOX)療法を施行した。4コース後に肝転移,腹膜播種および左腰部に皮下転移を認めた。皮下病変の針生検により免疫組織学的に転移と確認された。術後から8か月で死亡した。直腸癌の皮下転移は比較的まれであり報告する。