内容紹介
Summary
A 57-year-old female was referred to our hospital due to a palpable tumor of the left breast; she was diagnosed with cancer in the left breast 3 years prior, in 201X. After the administration of FEC and docetaxel plus trastuzumab as preoperative chemotherapy, left mastectomy with axillary lymph node dissection was performed, and irradiation and trastuzumab were administered postoperatively for 1 year. During the observation, there was skin thickening around the right nipple. A skin biopsy was then performed in 201X, and the patient was diagnosed with diffuse large B-cell lymphoma(DLBCL). PET-CT revealed a slight accumulation in the peripheries of the right nipple and mammary glands. Core needle biopsy of the tumor in the mammary gland showed DLBCL similar to that observed in the skin biopsy. Imaging revealed complete response after chemotherapy, whole-body irradiation, and intrathecal administration. Currently, both breast cancer and DLBCL of the breast have not relapsed.
要旨
症例は57歳,女性。201X-3年に左乳癌と診断された。術前化学療法(FEC→docetaxel+trastuzumab)施行後,左乳房切除術+腋窩リンパ節郭清と術後放射線治療,trastuzumab投与を計1年間施行した。201X年,右乳頭周囲に皮膚の肥厚が出現し,皮膚生検にてびまん性大細胞型B細胞リンパ腫(DLBCL)と診断された。PET-CTにて右乳頭周囲,乳腺外側領域に中等度の集積を認め,針生検で皮膚同様のDLBCLと診断された。化学療法,放射線治療,髄注療法を行い,画像上CRを得られた。現在,乳癌・乳腺DLBCLとも無再発生存中である。
目次
A 57-year-old female was referred to our hospital due to a palpable tumor of the left breast; she was diagnosed with cancer in the left breast 3 years prior, in 201X. After the administration of FEC and docetaxel plus trastuzumab as preoperative chemotherapy, left mastectomy with axillary lymph node dissection was performed, and irradiation and trastuzumab were administered postoperatively for 1 year. During the observation, there was skin thickening around the right nipple. A skin biopsy was then performed in 201X, and the patient was diagnosed with diffuse large B-cell lymphoma(DLBCL). PET-CT revealed a slight accumulation in the peripheries of the right nipple and mammary glands. Core needle biopsy of the tumor in the mammary gland showed DLBCL similar to that observed in the skin biopsy. Imaging revealed complete response after chemotherapy, whole-body irradiation, and intrathecal administration. Currently, both breast cancer and DLBCL of the breast have not relapsed.
要旨
症例は57歳,女性。201X-3年に左乳癌と診断された。術前化学療法(FEC→docetaxel+trastuzumab)施行後,左乳房切除術+腋窩リンパ節郭清と術後放射線治療,trastuzumab投与を計1年間施行した。201X年,右乳頭周囲に皮膚の肥厚が出現し,皮膚生検にてびまん性大細胞型B細胞リンパ腫(DLBCL)と診断された。PET-CTにて右乳頭周囲,乳腺外側領域に中等度の集積を認め,針生検で皮膚同様のDLBCLと診断された。化学療法,放射線治療,髄注療法を行い,画像上CRを得られた。現在,乳癌・乳腺DLBCLとも無再発生存中である。