内容紹介
Summary
Objectives: Resection of lung metastasis in colorectal cancer leads to a good prognosis; therefore, surgical treatment for resectable metastases is recommended by the Japanese Society for Cancer of the Colon and Rectum Guidelines for the treatment of colorectal cancer. In this study, we investigated the factors that affect the prognosis of resection of such lung cancers. Results: Outcomes of 23 cases of lung resection performed from 2000 to 2019 were investigated. The 5-year overall survival rate after lung resection was 55.5%, and the 5-year relapse-free survival rate after liver resection was 27.0%. Univariate analysis identified sex(p=0.024), tumor size(p=0.0129)and complications(p=0.0129)as prognostic factors, while multivariate analysis revealed sex(p=0.0278, relative risk=5.38)to be a prognostic factor. Conclusion: In this study, sex was identified as a poor prognostic factor. Further evidence from cases is needed to ascertain the effects of other factors.
要旨
目的: 切除可能な大腸癌肺転移は良好な予後が得られることが知られており,大腸癌治療ガイドラインにおいても手術治療が推奨されている。今回われわれは,その予後に影響を与える因子につき検討した。結果: 2000～2019年までの肺切除23例を対象とした。5年overall survival 55.5%,5年relapse-free survivalは27.0%であった。単変量解析では性別(p=0.024),術後合併症(p=0.0129),腫瘍径(p=0.0129)が予後規定因子として抽出され,多変量解析では性別(p=0.0278,RR=5.38)が抽出された。結論: 今回の解析では性別が予後不良因子として抽出された。今後さらなる症例の集積が必要である。
目次
Objectives: Resection of lung metastasis in colorectal cancer leads to a good prognosis; therefore, surgical treatment for resectable metastases is recommended by the Japanese Society for Cancer of the Colon and Rectum Guidelines for the treatment of colorectal cancer. In this study, we investigated the factors that affect the prognosis of resection of such lung cancers. Results: Outcomes of 23 cases of lung resection performed from 2000 to 2019 were investigated. The 5-year overall survival rate after lung resection was 55.5%, and the 5-year relapse-free survival rate after liver resection was 27.0%. Univariate analysis identified sex(p=0.024), tumor size(p=0.0129)and complications(p=0.0129)as prognostic factors, while multivariate analysis revealed sex(p=0.0278, relative risk=5.38)to be a prognostic factor. Conclusion: In this study, sex was identified as a poor prognostic factor. Further evidence from cases is needed to ascertain the effects of other factors.
要旨
目的: 切除可能な大腸癌肺転移は良好な予後が得られることが知られており,大腸癌治療ガイドラインにおいても手術治療が推奨されている。今回われわれは,その予後に影響を与える因子につき検討した。結果: 2000～2019年までの肺切除23例を対象とした。5年overall survival 55.5%,5年relapse-free survivalは27.0%であった。単変量解析では性別(p=0.024),術後合併症(p=0.0129),腫瘍径(p=0.0129)が予後規定因子として抽出され,多変量解析では性別(p=0.0278,RR=5.38)が抽出された。結論: 今回の解析では性別が予後不良因子として抽出された。今後さらなる症例の集積が必要である。