内容紹介
Summary
A 44—year—old woman experienced loss of vision and distorted vision in the right eye. After she visited our hospital, she was diagnosed with a right metastatic choroidal tumor. At the age of 35 years, she had undergone surgery for left breast cancer;as recurrence of the breast cancer was suspected, the patient was referred to our department. A CT scan revealed left axillary lymph node swelling, liver metastasis, and lung metastasis. Lymph node needle biopsy was performed under ultrasound guidance, and the pathological findings revealed recurrence of breast cancer. Combination chemotherapy of bevacizumab(BV)plus paclitaxel(PTX)was administered. After chemotherapy, the metastatic lesion had remarkably shrunk, as observed on a CT scan. Optical coherence tomography(OCT)revealed that the tumor was flattened in her right eye. Choroidal metastasis of breast cancer is rare. BV plus PTX therapy was effective for treating choroidal metastasis of breast cancer, and it should be followed by ophthalmological examination over time.
要旨
症例は44歳,女性。右眼の視力低下を主訴に眼科を受診され,右転移性脈絡膜腫瘍と診断された。35歳時に左乳癌手術治療歴があり,乳癌の再発が疑われ当科を紹介受診となった。CTにて左腋窩リンパ節,肝転移,肺転移を認めた。超音波下リンパ節針生検標本から病理組織学的検索を行い,乳癌術後再発と診断した。bevacizumab(BV)+paclitaxel(PTX)併用療法を施行し,CTにて転移巣は著明に縮小を認めた。光干渉断層計(optical coherence tomography:OCT)にて脈絡膜転移巣の縮小を確認でき,眼症状も改善した。まれな乳癌脈絡膜転移症例に対して化学療法を行い眼症状が軽快し,OCTで治療効果が追えた1例を経験したので報告する。
目次
A 44—year—old woman experienced loss of vision and distorted vision in the right eye. After she visited our hospital, she was diagnosed with a right metastatic choroidal tumor. At the age of 35 years, she had undergone surgery for left breast cancer;as recurrence of the breast cancer was suspected, the patient was referred to our department. A CT scan revealed left axillary lymph node swelling, liver metastasis, and lung metastasis. Lymph node needle biopsy was performed under ultrasound guidance, and the pathological findings revealed recurrence of breast cancer. Combination chemotherapy of bevacizumab(BV)plus paclitaxel(PTX)was administered. After chemotherapy, the metastatic lesion had remarkably shrunk, as observed on a CT scan. Optical coherence tomography(OCT)revealed that the tumor was flattened in her right eye. Choroidal metastasis of breast cancer is rare. BV plus PTX therapy was effective for treating choroidal metastasis of breast cancer, and it should be followed by ophthalmological examination over time.
要旨
症例は44歳,女性。右眼の視力低下を主訴に眼科を受診され,右転移性脈絡膜腫瘍と診断された。35歳時に左乳癌手術治療歴があり,乳癌の再発が疑われ当科を紹介受診となった。CTにて左腋窩リンパ節,肝転移,肺転移を認めた。超音波下リンパ節針生検標本から病理組織学的検索を行い,乳癌術後再発と診断した。bevacizumab(BV)+paclitaxel(PTX)併用療法を施行し,CTにて転移巣は著明に縮小を認めた。光干渉断層計(optical coherence tomography:OCT)にて脈絡膜転移巣の縮小を確認でき,眼症状も改善した。まれな乳癌脈絡膜転移症例に対して化学療法を行い眼症状が軽快し,OCTで治療効果が追えた1例を経験したので報告する。